What Foods to Avoid During Chemotherapy

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As a dietitian working in oncology care, Registered Dietitian, Melanie Mitchell, is often asked, “What foods should I avoid while on chemotherapy?”

When appetite is poor and symptoms such as nausea and changes in taste are present, it can be difficult to feel interested in food at all. For this reason, I keep the list of “foods to avoid” as short as possible—because eating something is almost always better than eating nothing.

It’s also important to note that different treatments, cancer types, and individual circumstances create unique nutrition challenges. For personalized guidance, I encourage you to seek the advice of a registered dietitian. In the meantime, below are general food safety and tolerance considerations for people receiving chemotherapy.


Foods to Avoid (or Use Caution With) During Chemotherapy

Uncooked or Partially Cooked Meats, Fish, and Eggs

During chemotherapy, your immune system may be weakened, increasing the risk of foodborne illness. To reduce this risk:

  • Cook meat and poultry to an internal temperature of 165°F
  • Cook fish to 145°F
  • Cook eggs until both the white and yolk are firm
  • Avoid foods left at room temperature for more than two hours
  • Reheat leftovers to 165°F and consume within 3–5 days, even if refrigerated
  • Avoid unpasteurized milk or juices, which may contain harmful bacteria

Grapefruit

Grapefruit and grapefruit juice contain compounds that interfere with the metabolism of several chemotherapy and cancer-related medications. For this reason, grapefruit should be avoided during chemotherapy unless your care team confirms it is safe.

Fried Foods

Fried and greasy foods (such as hamburgers, French fries, and chicken fingers) are not harmful, but they can be difficult to digest during chemotherapy. These foods may worsen symptoms such as bloating, gas, indigestion, or diarrhea. If you’re craving fried foods, consider starting with a half portion. This can help satisfy the craving while minimizing digestive discomfort.

Spicy Foods

Spicy foods are also not harmful, but they may irritate a sensitive mouth or throat and can contribute to indigestion or mouth pain. If spicy flavors are appealing—especially if they are among the few flavors you can taste—start with a small amount to see how well you tolerate them before eating a full serving.

Unwashed Raw Fruits and Vegetables

Raw fruits and vegetables are nutritious but can harbor bacteria if not cleaned properly.

  • Rinse all produce under running water for at least one minute
  • Wash fruits with skins (such as bananas, melons, avocados, oranges, and lemons), since germs on the peel can transfer to your hands and use a clean produce brush when appropriate
  • For extra caution, vegetables can be blanched (boiled for 3–4 minutes), which kills bacteria while preserving fiber

If you have questions about which foods are best for you during your cancer journey, please ask your physician for a referral to schedule an appointment with Melanie Mitchell, CPN Registered Dietitian.

 

Healthy Holiday Eating Tips

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The holiday season can be a busy time—and it can also make it challenging to stick to your healthy eating habits. With a little mindfulness and a few simple strategies, you can enjoy the season without losing sight of your health.

Here are some practical tips to help you stay balanced and energized:

  1. Make Time to Move – Small bursts of activity can make a big difference. Take a brisk walk after lunch, stretch between tasks, or turn on some music and dance while you’re cooking. Movement helps manage stress, boosts energy, and keeps your metabolism active.
  2. Don’t Skip Meals – It might be tempting to “save up” for a big holiday dinner, but skipping meals often leads to overeating later. A helpful guideline: try to fill half your plate with vegetables. This keeps you satisfied and ensures you’re getting plenty of nutrients.
  3. Start Your Day with a Mindful Breakfast – Set the tone for your day by slowing down in the morning. Sit for at least five minutes while enjoying a nourishing breakfast. Taking time to eat mindfully helps you feel grounded and less likely to grab sugary snacks later.
  4. Don’t Skip Fruit – Holiday sweets are everywhere, but adding fruit to your day can help curb sugar cravings. Try having an apple, an orange, or a handful of berries before indulging in cookies or pie. The natural sweetness satisfies your taste buds while giving your body fiber and vitamins.
  5. Stay Hydrated – With all the festive drinks around, it’s easy to forget about water. Keep a reusable bottle nearby and sip throughout the day. Hydration supports digestion, helps control appetite, and keeps you feeling refreshed.

Healthy eating during the holidays doesn’t mean missing out—it means making mindful choices that help you feel your best.

 

CPN Welcomes Dr. Swetha Yadav, Medical Oncologist

The Key to Hydration

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Staying well-hydrated during your cancer treatment is extremely important. Fluid losses through sweat, vomiting, diarrhea, or other circumstances can result in dehydration quickly. You may become dehydrated before you experience any symptoms of dehydration. Symptoms include thirst, dizziness, dark-color urine, and headaches. Preventing dehydration will not only make you feel better but also help avoid any serious situations that would require medical attention. A general goal is 8-10 cups of caffeine-free fluid daily unless you are experiencing diarrhea, vomiting or excessive sweating, in which case you may require more fluid and electrolytes.

Strategies to Avoid Dehydration

 

Below are suggestions for electrolyte replacement beverages.

 

Product Calories Sodium Potassium Vitamins
Liquid IV (packet) 45 500 mg 370 mg B vitamins
Nuun Sport (tab) 15 300 mg 150 mg Mild Flavor
Pedialyte (packet) 50 540 mg 380 mg
Protein2O (bottle) 80 220 mg 110 mg 15 g protein
Ensure Clear (bottle) 180 70 mg minimal 8 g protein

 

Thirst Quenching Watermelon Salad

3 Tablespoons Lime Juice           3 cups cubed cucumber

1 cup sliced Red Onion                1 ounce Feta Cheese Crumbled

15 cups cubed Watermelon         ¼ cup chopped Mint Leaves

Marinate the onions in the lime juice while cubing watermelon and cucumber. Combine all the ingredients in a large bowl and mix well. Place the salad in the fridge for 1 hour to combine all the flavors. Enjoy!

CPN Welcomes Dr. Justin Burr, Radiation Oncologist

CPN Welcomes Dr. Kathryn Kennedy, Gynecologic Oncology Surgeon

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